Trapped Chromatin Fibers Damage Flowing Red Blood Cells
نویسندگان
چکیده
منابع مشابه
Velocity profiles of blood platelets and red blood cells flowing in arterioles of the rabbit mesentery.
Velocity profiles were determined in rabbit mesenteric arterioles (diameter 17-32 micron). A good spatial resolution was obtained by using the blood platelets as small and natural markers of flow, providing for the first time in vivo detailed, quantitative information about the shape of the velocity profiles in microvessels. In some experiments red blood cell velocity profiles were recorded as ...
متن کاملBlood platelets are concentrated near the wall and red blood cells, in the center in flowing blood.
Hematocrit and vessel wall shear rate are important factors in the transport and subsequent adherence of platelets to vessel wall subendothelium. When mass transport theory is applied to platelets in flowing blood, the blood is usually considered to be a fluid with platelet and red cell wall concentrations similar to the average tube concentration. With the laser-Doppler technique, we found how...
متن کاملEffect of aggregation and shear rate on the dispersion of red blood cells flowing in venules.
Previous in vitro studies of blood flow in small glass tubes have shown that red blood cells exhibit significant erratic deviations in the radial position in the laminar flow regime. The purpose of the present study was to assess the magnitude of this variability and that of velocity in vivo and the effect of red blood cell aggregation and shear rate upon them. With the use of a gated image int...
متن کاملA Biophotonic Study of Live, Flowing Red Blood Cells in an Optical Trap
We investigate the physics of an optically trapped red blood cell under physiological conditions. When a single, live red blood cell, is placed in an optical trap, the normal biconcave disk shaped cell is observed to undergo a folding action and thereby take up a rod like shape. If such an RBC has any shape anisotropies due to perturbation through malarial infection or hyperosmotic stress, it i...
متن کاملA methodology to study the deformability of red blood cells flowing in microcapillaries in vitro.
The deformability of red blood cells flowing in microvessels is essential to maintain optimal blood circulation and to allow gas transfer between blood and tissues. Here, we report on an experimental methodology to investigate the deformability of RBCs flowing in microcapillaries having diameter close to the average cell size. The microcapillaries are placed in a rectangular flow cell, where a ...
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ژورنال
عنوان ژورنال: Advanced Biosystems
سال: 2018
ISSN: 2366-7478,2366-7478
DOI: 10.1002/adbi.201800040